过去一年中添加的文章,按日期排序

Natural Killer Cell Dysfunction In Human Bladder Cancer Is Caused By Tissue-Specific Suppression of SLAMF6 Signaling

AM Farkas, MA Tran, D Youssef, S Balan, JH Newman… - bioRxiv, 2024 - biorxiv.org
8 天前 - targets that improve response 51 rates. Natural Killer cells (NK) are innate
lymphocytes … and tumor, we analyzed tumor tissue and 71 peripheral blood mononuclear cells (…

Optimisation of a primary human CAR‐NK cell manufacturing pipeline

A Pfefferle, J Contet, K Wong, C Chen… - Clinical & …, 2024 - Wiley Online Library
10 天前 - … on-target cytotoxicity make peripheral blood-derived NK cells a … NK cells are innate
cytotoxic lymphocytes of relatively short … Natural killer cells were isolated from either fresh or …

GZMK-expressing Immune Cells in Chronic Obstructive Pulmonary Disease

S Matsumoto, T Numakura, M Yamada… - … THE PANDORA BOX, 2024 - atsjournals.org
10 天前 - … + T cells are a subset of cytotoxic lymphocytes that accumulate in the peripheral
blood and … Targeting GZMK or PAR1 could be a promising therapeutic strategy to modulate the …

BCL2A1 neoepitopes-elicited cytotoxic T lymphocytes are a promising individualized immunotherapy of pancreatic cancer

S Lin, J Hong, S Wu, C Zhu, F Liu, W Lin… - Journal of Leukocyte …, 2024 - academic.oup.com
25 天前 - … In this study, cancer specimen and peripheral blood were sampled from a human
28 … presented a 20 comparable cytotoxicity against target cells at various effector to target

[HTML][HTML] Impact of doxorubicin-loaded ferritin nanocages (FerOX) vs. free doxorubicin on T lymphocytes: a translational clinical study on breast cancer patients …

M Sevieri, F Andreata, F Mainini, L Signati… - Journal of …, 2024 - Springer
26 天前 - lymphocytes from healthy donors. We found that patient-derived peripheral blood
mononuclear cells … This investigation aimed to understand how each subset responds to DOX, …

Abstract LB074: Preclinical development of API-192: An engineered CAR-NKT allogeneic cell therapy targeting CD19 and CD20 for the treatment of B-cell …

L Gov, J Yu, M Qubain, SL Pompura, SD Allen… - Cancer Research, 2024 - AACR
36 天前 - … and elicits less interferon (IFN)-γ release by NK and T cells in a mixed lymphocyte
… co-culture with healthy donor peripheral blood mononuclear cells, consistent with a low graft …

rhIL-7-hyFc (efineptakin-alfa, NT-I7) increases tumor-specific CD8+ T cells despite FOLFOX cytotoxicity effect

SM Lee, M Kim, S Ferrando-Martínez, SK Im, M Ji… - Cancer Research, 2024 - AACR
50 天前 - … the number of CD8+ T cells in peripheral blood but also dramatically boosts the …
newly dividing lymphocytes during NT-I7 treatment (4-6). Therefore, in this study, we aimed to …

A cytolytic effector CD8+ T cell response is associated with remission in adult T-cell leukemia/lymphoma

E Guillen, E Liu, Y Wang, A Shastri, A Sica, A Verma… - Cancer Research, 2024 - AACR
50 天前 - … Furthermore, HTLV1-specific CD8+ cytotoxic T lymphocytes (CTLs) play an
important … collected during a phase 2 clinical trial aimed to assess the efficacy of a promising …

Vitokine-2: A TIL-targeting tumor activable engineered IL-2 for cancer treatment

SV Challa, YT Hsieh, K Gelinas, A Umana, W Weng… - Cancer Research, 2024 - AACR
50 天前 - … NK cells using human peripheral blood mononuclear cells (… specific to cytotoxic
lymphocytes but not regulatory T cells. … functionality of CD8+ T cells in TME, robust antitumor …

[HTML][HTML] A single bout of vigorous intensity exercise enhances the efficacy of rituximab against human chronic lymphocytic leukaemia B-cells ex vivo

HD Collier-Bain, A Emery, AJ Causer, FF Brown… - Brain, Behavior, and …, 2024 - Elsevier
56 天前 - … a transient relocation of NK-cells and B-cells into peripheral blood, which could be
… in CLL by relocating both target and effector cells together with rituximab in blood. In this pilot …